Season 4, Episode 15
In a quiet town people have stopped dying no matter what injuries or illnesses they incur. What could be stopping Reapers from gathering souls?
Dean: No, this not devil worship. It's...it's...uh....I don't have a good answer.
Sam: What are we going to do? Just swing in and save the friendly neighborhood Reaper?
Alastair: It's hard to get it up when you're not wearing your meat.
Dean: If you want our help, why the hell didn't you just ask?
Castiel: Because whatever I ask, you seem to do the exact opposite.